Jean Gudas,Aya Jakobovits,Zili An,Robert Kendall Morrison,Karen Jane Meyrick Morrison,Xiao-chi Jia,Dennis Benjamin,Ruth Moser,Peter Senter
申请号：
US12718902
公开号：
US08309093B2
申请日:
2010.03.05
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Antibody drug conjugates (ADCs) that bind to 24P4C12 protein and variants thereof are described herein. 24P4C12 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, the ADCs of the invention provide a therapeutic composition for the treatment of cancer.
