BARUCH S. BLUMBERG INSTITUTE;ENANTIGEN THERAPEUTICS, INC.;DREXEL UNIVERSITY
发明人:
BAUGH, SIMON DAVID PETER,YE, HONG,XU, XIAODONG,GUO, JU-TAO,XIAO, TONG,DU, YANMING,BLOCK, TIMOTHY
申请号:
EP13868405
公开号:
EP2938338A4
申请日:
2013.12.27
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
The present invention provides novel compounds of formula (I) and methods of use thereof. In certain embodiments, the compounds of the invention are useful as nucleocapsid assembly inhibitors. In other embodiments, the compounds of the invention are useful as pregenomic RNA encapsidation inhibitors of Hepatitis B virus (HBV). In yet other embodiments, the compounds of the invention are useful for the treatment of viral infection, including HBV and related viral infections.