BARUCH S. BLUMBERG INSTITUTE;ENANTIGEN THERAPEUTICS, INC.;DREXEL UNIVERSITY
发明人:
XU, XIAODONG,GUO, JU-TAO,XIAO, TONG,DU, YANMING,BLOCK, TIMOTHY,BAUGH, SIMON DAVID PETER,YE, HONG
申请号:
SG11201504740U
公开号:
SG11201504740UA
申请日:
2013.12.27
申请国别(地区):
SG
年份:
2015
代理人:
摘要:
The present invention provides novel compounds of formula (I) and methods of use thereof. In certain embodiments, the compounds of the invention are useful as nucleocapsid assembly inhibitors. In other embodiments, the compounds of the invention are useful as pregenomic RNA encapsidation inhibitors of Hepatitis B virus (HBV). In yet other embodiments, the compounds of the invention are useful for the treatment of viral infection, including HBV and related viral infections.