BARUCH S. BLUMBERG INSTITUTE;ENANTIGEN THERAPEUTICS, INC.;DREXEL UNIVERSITY
发明人:
HONG YE,JU-TAO GUO,SIMON DAVID PETE BAUGH,TIMOTHY BLOCK,TONG XIAO,XIADONG XU,YANMING DU
申请号：
BR112015015584
公开号：
BR112015015584A2
申请日:
2013.12.27
申请国别(地区):
BR
年份:
2017
代理人:
摘要：
The present invention provides novel compounds of formula (I) and methods of use thereof. In certain embodiments, the compounds of the invention are useful as nucleocapsid assembly inhibitors. In other embodiments, the compounds of the invention are useful as pregenomic RNA encapsidation inhibitors of Hepatitis B virus (HBV). In yet other embodiments, the compounds of the invention are useful for the treatment of viral infection, including HBV and related viral infections.
