STABLE POLYPEPTIDES BINDING TO HUMAN COMPLEMENT C5

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专利权人:

SWEDISH ORPHAN BIOVITRUM AB (PUBL)

发明人:

NILSSON, JOAKIM,NORDLING, ERIK,STRÖMBERG, PATRIK

申请号：

SG11201602679V

公开号：

SG11201602679VA

申请日:

2014.08.28

申请国别(地区):

SG

年份:

2016

代理人:

摘要：

The invention relates to a polypeptide capable of binding human complement component 5 (C5), said polypeptide comprising the amino acid sequence [BM]-[L2]-QSX42X43LLX46EAKKLX52X53X54Q wherein [BM] is a C5 bindingmotif； [L2] is an interconnecting loop； X42 is selected from A and S； X43 is selected from N and E； X46 is selected from A, S and C； X52 is selected from E, N and S； X53 is selected from D, E and S, provided that X53 is not D when X52 is N； and X54 is selected from A and S.

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