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STABLE POLYPEPTIDES BINDING TO HUMAN COMPLEMENT C5
专利权人:
发明人:
NILSSON JOAKIM,NORDLING ERIK,STR–MBERG PATRIK
申请号:
IN201617010380
公开号:
IN201617010380A
申请日:
2016.03.26
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
The invention relates to a polypeptide capable of binding human complement component 5 (C5), said polypeptide comprising the amino acid sequence [BM]-[L2]-QSX42X43LLX46EAKKLX52X53X54Q wherein [BM] is a C5 bindingmotif [L2] is an interconnecting loop X42 is selected from A and S X43 is selected from N and E X46 is selected from A, S and C X52 is selected from E, N and S X53 is selected from D, E and S, provided that X53 is not D when X52 is N and X54 is selected from A and S.
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