Gregory Breyta,Julian M.W. Chan,Daniel J. Coady,Amanda C. Engler,Jeannette M. Garcia,Wei Han,James L. Hedrick,Shaoqiong Liu,Alshakim Nelson,Robert J. Ono,Jye Yng Teo,Yi Yan Yang,Mu San Zhang
申请号:
US14705451
公开号:
US20160326319A1
申请日:
2015.05.06
申请国别(地区):
US
年份:
2016
代理人:
摘要:
A number of cationic antimicrobial polymers have been synthesized by a condensation polymerization in bulk. The initial polymer formed has backbone tertiary nitrogens, which are subsequently quaternized using a suitable quaternizing agent (e.g., alkyl halide). The cationic polymers include polyamides, polycarbonates, polypolyureas and polyguanidiniums having a cationic repeat unit comprising the quaternary ammonium nitrogen as a backbone nitrogen. The cationic polymers can be active against Gram-negative, Gram-positive microbes, and/or fungi.