Gregory Breyta,Julian M. W. Chan,Daniel J. Coady,Amanda C. Engler,Jeannette M. Garcia,Wei Han,James L. Hedrick,Alshakim Nelson,Robert J. Ono,Yi Yan Yang,Mu San Zhang
申请号:
US15361313
公开号:
US10023697B2
申请日:
2016.11.25
申请国别(地区):
US
年份:
2018
代理人:
摘要:
A number of cationic antimicrobial polymers have been synthesized by a condensation polymerization in bulk. The initial polymer formed has backbone tertiary nitrogens, which are subsequently quaternized using a suitable quaternizing agent (e.g., alkyl halide). The cationic polymers include polyamides, polycarbonates, polypolyureas and polyguanidiniums having a cationic repeat unit comprising the quaternary ammonium nitrogen as a backbone nitrogen. The cationic polymers can be active against Gram-negative, Gram-positive microbes, and/or fungi.