Daniel J. Coady,Amanda C. Engler,Jeanette M. Garcia,James L. Hedrick,Jeremy P.K. Tan,Yi Yan Yang
申请号：
US14223630
公开号：
US20150264932A1
申请日:
2014.03.24
申请国别(地区):
US
年份:
2015
代理人:
摘要：
Eight-membered ring cyclic carbonates comprising a ring nitrogen at position 6 (1,3,6-dioxazocan-2-ones) were prepared by reaction of precursor diols with active carbonates. The ring nitrogen is linked to a pendant group Y′ via a methylene linking group. The cyclic carbonates undergo organocatalyzed ring opening polymerization to form an initial polycarbonate comprising a backbone tertiary amine group. Quaternization of the initial polycarbonates forms cationic polycarbonates comprising a positive-charged backbone quaternary nitrogen. The cationic polycarbonates can be potent antimicrobial agents.
