BioNTech RNA Pharmaceuticals GmbH;TRON - Translationale Onkologie an der Universitatsmedizin der Johannes Gutenberg-Universitat Mainz gemeinnutzige GmbH
发明人:
Sahin, Ugur,Tadmor, Arbel David,Castle, John Christopher,Boegel, Sebastian,Lower, Martin
申请号:
AU2014264943
公开号:
AU2014264943B2
申请日:
2014.05.07
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
The present invention relates to methods for predicting T cell epitopes. In particular, the present invention relates to methods for predicting whether modifications in peptides or polypeptides such as tumor-associated neoantigens are immunogenic or not. The methods of the invention are useful, in particular, for the provision of vaccines which are specific for a patient's tumor and. thus, in the context of personalized cancer vaccines.