TRON - TRANSLATIONALE ONKOLOGIE AN DER UNIVERSITÄ- TSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITÄT MAIN;BIONTECH AG
发明人:
Ugur Sahin,Arbel David Tadmor,John Christopher Castle,Sebastian Boegel,Martin Löwer
申请号:
US14787110
公开号:
US20160125129A1
申请日:
2014.05.07
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to methods for predicting T cell epitopes. In particular, the present invention relates to methods for predicting whether modifications in peptides or polypeptides such as tumor-associated neoantigens are immunogenic or not. The methods of the invention are useful, in particular, for the provision of vaccines which are specific for a patient's tumor and, thus, in the context of personalized cancer vaccines.