TRON - TRANSLATIONALE ONKOLOGIE AN DER UNIVERSITÄTSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITÄT MAINZGEMEINNÜTZIGE GMBH;BIONTECH AG;UNIVERSITÄTSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITÄT MAINZ
发明人:
SAHIN, UGUR,TADMOR, ARBEL DAVID,CASTLE, JOHN CHRISTOPHER,BOEGEL, SEBASTIAN,LÖWER, MARTIN
申请号:
SG11201508816R
公开号:
SG11201508816RA
申请日:
2014.05.07
申请国别(地区):
SG
年份:
2015
代理人:
摘要:
The present invention relates to methods for predicting T cell epitopes. In particular, the present invention relates to methods for predicting whether modifications in peptides or polypeptides such as tumor-associated neoantigens are immunogenic or not. The methods of the invention are useful, in particular, for the provision of vaccines which are specific for a patient's tumor and, thus, in the context of personalized cancer vaccines.