A system and method associates a syringe and an attached spike with a corresponding vial and the medicinal composition contained in the vial. The system includes a labeled seal that detachably attaches to a spike and is removed for attachment to syringe. The labeled seal has an identifier, such as a color-coding, a tactile, or textual indicia. These identifiers on the labeled seal matches identifiers on a vial label that attaches to a vial containing the medicinal composition. The matching identifiers on the labeled seal and the vial label enable association between the syringe and the vial, so as to utilize the appropriate medicinal composition with the syringe. The identifier on the labeled seal is also indicative of the medicinal composition in the vial. A second label locks between the syringe and spike. The second label also serves to match the syringe with the corresponding vial and medicinal composition.