Ophthalmic formulations comprising an a1 agonist

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专利权人:

Inotek Pharmaceuticals Corporation

发明人:

Harun Takruri,Mcvicar William K.

申请号：

NZ63075914

公开号：

NZ630759A

申请日:

2014.03.14

申请国别(地区):

NZ

年份:

2017

代理人:

摘要：

Provided are ophthalmic formulations comprising ((2R,3S,4R,5R)-5-(6-(cyclopentylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl nitrate and boric acid. Boric acid improves the stability of ((2R,3S,4R,5R)-5-(6-(cyclopentylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl nitrate and reduces particle growth when the formulations are in storage.

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