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PHARMACEUTICAL COMPOSITION COMPRISING 6-(4-BROMO-2-CHLORO-PHENYLAMINO)-7-FLUORO-3-METHYL-3H-BENZOIMIDAZOLE-5-CARBOXYLIC ACID (2-HYDROXY-ETHOXY)-AMIDE
专利权人:
ASTRAZENECA AB
发明人:
BATEMAN, NICOLA, FRANCES,GELLERT, PAUL, RICHARD,HILL, KATHRYN, JANE
申请号:
NZ58884909
公开号:
NZ588849A
申请日:
2009.03.26
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed is a pharmaceutical composition comprising a hydrogen sulphate salt of 6-( 4-bromo-2-chloro-phenylamino )-7 -fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid (2-hydroxy-ethoxy)-amide, and a carrier matrix comprising one or more pharmaceutically acceptable carriers selected from the following groups: (a) d-alpha-tocopheryl polyethylene glycol 1000 succinate (b) polyglycolised glycerides (c) polyethylene glycols (PEGs) and (d) hard fats and wherein the hydrogen sulphate salt of 6-( 4-bromo-2-chloro-phenylamino )-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid (2-hydroxy-ethoxy)-amide is dispersed within the carrier matrix. The pharmaceutical composition is used to treat cancer.
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