VAUGHN, ERIC MARTIN,BUCKLIN, SCOTT EUGENE,KAISER, TROY JAMES,KROLL, JEREMY,UTLEY, PHILIP
申请号:
CA3042573
公开号:
CA3042573A1
申请日:
2017.11.02
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The present invention relates i.a. to a porcine parvovirus (PPV) viral protein 2 (VP2) having at amino acid position 228 a glutamic acid residue or a glutamate residue, and/or at amino acid position 414 a serine residue, and/or at amino acid position 419 a glutamine residue, and/or at amino acid position 436 a threonine residue. Further, the present invention relates to immunogenic compositions comprising said PPV viral protein 2 (VP2). Furthermore, the present invention relates to methods for immunizing a subject comprising administering to such subject the immunogenic composition of the present invention. Moreover, the present invention relates to methods of treating or preventing clinical signs caused by PPV infection in a subject of need, the method comprising administering to the subject a therapeutically effective amount of an immunogenic composition according to the present invention.