LI, YUN-LONG,李裕隆,RODGERS, JAMES D.,洛德杰斯 詹姆斯Ｄ,洛德傑斯 詹姆斯Ｄ,洛德杰斯 詹姆斯D,洛德傑斯 詹姆斯D
申请号：
TW099116415
公开号：
TWI484962B
申请日:
2010.05.21
申请国别(地区):
TW
年份:
2015
代理人:
摘要：
The present invention relates to the Janus kinase (JAK) inhibitors 3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]octanenitrile or 3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]heptanenitrile, as well as its compositions and methods of use, which is useful in the treatment of JAK-associated diseases including, for example, inflammatory and autoimmune disorders, skin disorders, cancer, and other diseases.本發明係關於詹納斯激酶(Janus kinase；JAK)抑制劑3-[4-(7H-吡咯并[2,3-d]嘧啶-4-基)-1H-吡唑-1-基]辛腈或3-[4-(7H-吡咯并[2,3-d]嘧啶-4-基)-1H-吡唑-1-基]庚腈，及其組合物與使用方法，其可用於治療與JAK相關的疾病，該等疾病包含例如炎症與自體免疫性疾病、皮膚病、癌症、及其他疾病。
