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Zastosowanie koniugatu kwasu żółciowego albo soli kwasu żółciowego z kwasem tłuszczowym oraz zastosowanie kompozycji farmaceutycznej zawierającej taki koniugat do obniżania poziomu cholesterolu we krwi
专利权人:
GALMED INTERNATIONAL LIMITED
发明人:
GILAT TUVIA
申请号:
PL38745802
公开号:
PL211438B1
申请日:
2002.04.15
申请国别(地区):
PL
年份:
2012
代理人:
摘要:
Use of a bile acid or bile salt fatty acid conjugate of general formula II W-X-G in which G is a bile acid or bile salt radical, which, if desired, is conjugated in position 24 with an amino acid, W stands for one or two fatty acid radicals having 14-22 carbon atoms and X stands for a suitable bonding member or for a direct C=C bond between said bile acid or bile salt radical and the fatty acid(s) or of a phannaceutical composition comprising same for the manufacture of a medicament for the reduction of the cholesterol in blood and for the treatment of hyperglycemia and diabetes, wherein said suitable bonding member provides a solid bond that is not substantially deconjugated during the absorption process of the conjugate.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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