SU, Zhuang,LONG, Zhengyu,HUANG, Zhennian,YANG, Suizhou
申请号：
ES11845460
公开号：
ES2625502T3
申请日:
2011.12.05
申请国别(地区):
ES
年份:
2017
代理人:
摘要：
A compound of formula (I): ** Formula ** or pharmaceutically acceptable salt thereof, wherein: R8 is n-butyl, (E) -but-2-enyl, or ** Formula ** R2 is ethyl, 1 -hydroxyethyl, isopropyl, or n-propyl； W is O or S； R3 is: (C1-C6) alkyl, optionally substituted by one or more R4 groups which may be the same or different； (C2-C6) alkenyl, optionally substituted by one or more groups that may be the same or different selected from halogen, hydroxy, amino, monoalkylamino and dialkylamino； (C2-C6) alkynyl, optionally substituted by one or one or more groups that may be the same or different selected from halogen, hydroxy, amino, monoalkylamino and dialkylamino； (C3-C7) cycloalkyl, optionally substituted by one or more groups that may be the same or different selected from halogen, hydroxy, amino, monoalkylamino and dialkylamino； phenyl or CH2-phenyl, optionally substituted by one or more groups that may be the same or different selected from halogen, hydroxy, (C1-C6) alkyl； R7 is ** Formula ** R5 is: H； (C1-C6) alkyl, optionally substituted by one or more R6 groups which may be the same or different； (C2-C6) alkenyl, optionally substituted by one or more groups that may be the same or different, selected from hydroxy, (C1-C6) alkyl, aryl, (CH2) pORA, O (CH2) mOH, O (CH2) mO ( CH2) mOH, O (CH2) mNRARB, O (CH2) mO (CH2) mNRARB, (CH2) pNRARB, (CH2) pNRC (CH2) mNRARB, (CH2) pNRC (CH2) mNRC (CH2) mNRARB, (CH2) pC (>； = O) NRARB, (CH2) pC (>； = O) ORA； (C2-C6) alkynyl, optionally substituted by one or one or more groups that may be the same or different selected from halogen, hydroxy, amino, monoalkylamino and dialkylamino； (C3-C7) cycloalkyl, optionally substituted by one or more groups that may be the same or different selected from halogen, hydroxy, amino, monoalkylamino and dialkylamino； phenyl or CH2-phenyl, optionally substituted by one or more groups that may be the same or different selected from halogen, hydroxy, (C1-C6) alkyl, (CH2) pORA, (CH2) pNRARB, (CH2) pC (>；
