Compound having the structure of the general formula (I) ** Formula ** in which R1 in each case is independently selected from H, halogen, or the groups selected from (C1-C12) alkyl, haloalkyl, cycloalkyl , alkylthio or the alkyl group (OSO2), in which each of these groups is optionally further substituted with suitable substituents selected from hydroxyl, oxo, halogen, thio, nitro, amino, alkyl, alkoxy, haloalkyl and haloalkoxy groups； R 'in each case is independently selected from halogen, alkyl, alkoxy, hydroxyl, haloalkyl, haloalkoxy, cyano, thioalkyl, cycloalkyl groups； m>； = 1-4； L>； = -O, -S, -NH； n>； = 0-4； R2 is selected from substituent groups consisting of hydrogen atom, hydroxyl, alkyl, cycloalkyl, oxo, C (O) OR5, -C (O) R5 or -C (O) NR6R7, wherein said alkyl and cycloalkyl groups are further substituted with one or more substituents selected from halogen, hydroxyl, alkyl or alkoxy groups； R3 and R4 are each independently selected from a hydrogen atom, alkyl, hydroxyl, alkoxy, cycloalkyl, -C (O) OR5, -OC (O) R5, -O (CH2) pC (O) OR5 , -C (O) R5, -NHC (O) R5, -NR6R7, -OC (O) NR6R7 or -C (O) NR6R7, or alternatively, R3 and R4 together form an oxo group； each of the atoms of the ring "D" and "E" is independently selected from atoms of C or N； "D" and "E" are connected to each other to form a 5-member "X" ring, wherein "X" is selected from heterocyclyl and heteroaryl, wherein heterocyclyl and heteroaryl are substituted with one or more suitable substituents selected from hydrogen, cyano, halogen, hydroxyl, oxo, optionally substituted groups selected from alkyl, alkoxy, cycloalkyl, heterocyclyl, aryl, heteroaryl, benzyl, OR5, -C (O) OR5, -OC (O) R5, -O (CH2 ) pC (O) OR5, C (O) R5, S (O) qR5, -NHC (O) R5, NR6R7, -OC (O) NR6R7 or -C (O) NR6R7, and in which the alkyl group, cycloalkyl, heterocyclyl, aryl, heteroaryl or benzyl can each be, independently, also substituted with one or more substituents selected from the alkyl, halogen, hydroxyl, alkoxy, cycloa
