A Luer securement device comprising a flexible hood that is configured to attach to the surface of a patient, the flexible hood further having a Luer adapter for receiving a catheter inserter and/or a fluid line. The Luer securement device further includes a wedge seal that is positioned within the Luer adapter and is configured to receive a base portion of a catheter during a catheterization procedure. Once the base of the catheter is seated within the wedge seal, a proper insertion depth of the catheter into the patient is achieved.
