Provided is a method and apparatus for manufacturing nucleated tablets in each of which a nucleus is positioned in a precise manner. In the tablet manufacturing machine (1), granules are charged in a mortar and then compressed by pestles while the mortar and the pestles travel along a cyclic path extending from a point and then back to the point. The path has a substantially straight path portion where the mortar and the pestles travel substantially straightly.本發明的目的是提供一種:核可正確地定位之有核錠劑的製造方法及壓錠機。壓錠機(1),是在臼(5)與杵從特定位置沿著搬送路徑前進而回到該特定位置的期間,執行對臼(5)的粉體供給、及由杵對臼內粉體之壓縮的壓錠機。在搬送路徑設有:臼(5)與杵大致直線狀移動的直線部分(13、14)。1‧‧‧壓錠機2‧‧‧工作台3‧‧‧晶片供給裝置13、14‧‧‧直線部分(直線狀路徑)5‧‧‧臼100‧‧‧搬送路徑110‧‧‧粉體供給部(第1粉體供給部)120‧‧‧晶片供給部(核供給部)130‧‧‧粉體供給部(第2粉體供給部)140‧‧‧壓縮部150‧‧‧取出部