Friedrich NOLTE,Thomas EDEN,Janusz WESOLOWSKI,Stephan MENZEL
申请号:
US16467398
公开号:
US20200062833A1
申请日:
2017.12.08
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention contemplates isolated polynucleotide for the production of a VHH-containing heavy chain antibody in a mammal and vectors comprising said isolated polynucleotide. Moreover, the invention relates to a transgenic mammal comprising the vector for the production of a VHH-containing heavy chain antibody. Further, the invention relates to VHH-containing heavy chain antibodies as well as methods for the production and cloning of VHH-containing heavy chain antibodies.