Roger Kingdon Craig;ERASMUS UNIVERSITY MEDICAL CENTER ROTTERDAM
发明人:
Franklin Gerardus Grosveld,Richard Wilhelm Janssens,Roger Kingdon Craig
申请号:
US16848943
公开号:
US20200267951A1
申请日:
2020.04.15
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention relates to a method for the generation of VH heavy chain-only antibodies in a transgenic non-human mammal. In particular, the present invention relates to a method for the production of a VH heavy chain-only antibody in a transgenic non-human mammal comprising the step of expressing more than one heterologous VH heavy chain locus in that mammal.