ERASMUS UNIVERSITY MEDICAL CENTER ROTTERDAM;Roger Kingdon Craig
发明人:
Franklin Gerardus Grosveld,Richard Wilhelm Janssens,Roger Kingdon Craig
申请号：
US14962335
公开号：
US20160295843A1
申请日:
2015.12.08
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention relates to a method for the generation of VH heavy chain-only antibodies in a transgenic non-human mammal. In particular, the present invention relates to a method for the production of a VH heavy chain-only antibody in a transgenic non-human mammal comprising the step of expressing more than one heterologous VH heavy chain locus in that mammal.
