PROBLEM TO BE SOLVED: To provide a histidine-containing food or the like capable of providing a sufficient anti-fatigue effect even with a small content of histidine. A composition comprising (1) histidine and (2) vitamin B6 in combination at a blending ratio of histidine: vitamin B6 = 30: 1 to 240: 1. Furthermore, a packaged food containing the composition, and a packaged food in which the form of the food is a powder, a tablet, a granule, a capsule slurry, a solution, a jelly or an emulsion. [Selection diagram] None【課題】少ないヒスチジン含有量でも十分な抗疲労効果を提供し得る、ヒスチジン含有食品等の提供。【解決手段】(1)ヒスチジン及び(2)ビタミンB6を、ヒスチジン:ビタミンB6=30:1~240:1の配合割合で併用してなる組成物。更に、組成物を含有してなる容器詰食品、及び、食品の形態が粉末状、錠剤、顆粒状、カプセル状スラリー状、溶液状、ゼリー状または乳液状である、容器詰食品。【選択図】なし