The oxidation proteolytic enzyme active reinforcement conversion medicine is offered. The oxidation proteolytic enzyme active reinforcement conversion medicine of this invention features that at least the extract of one which is selected from the group which consists of chrysanthemum course antemisu being attached, dokudami course dokudami being attached, rosaceae sanzashi being attached and grape course grape being attached plant is included. As for the aforementioned oxidation proteolytic enzyme active reinforcement conversion medicine, it is desirable to include the extract of the chrysanthemum course antemisu being attached plant, the extract of the dokudami course dokudami being attached plant, the extract of the rosaceae sanzashi being attached plant and the extract of the grape course grape being attached plant. The aforementioned chrysanthemum course antemisu being attached plant is the Roman camomile, the aforementioned dokudami course dokudami being attached plant is dokudami, the aforementioned rosaceae sanzashi being attached plant is seiyousanzashi, as for the aforementioned grape course grape being attached plant, it is desirable to be the grape.酸化タンパク質分解酵素活性増強化剤を提供する。本発明の酸化タンパク質分解酵素活性増強化剤は、キク科アンテミス属、ドクダミ科ドクダミ属、バラ科サンザシ属およびブドウ科ブドウ属からなる群から選択される少なくとも一つの植物の抽出物を含むことを特徴とする。前記酸化タンパク質分解酵素活性増強化剤は、キク科アンテミス属の植物の抽出物、ドクダミ科ドクダミ属の植物の抽出物、バラ科サンザシ属の植物の抽出物およびブドウ科ブドウ属の植物の抽出物を含むことが好ましい。前記キク科アンテミス属の植物は、ローマカミツレであり、前記ドクダミ科ドクダミ属の植物は、ドクダミであり、前記バラ科サンザシ属の植物は、セイヨウサンザシであり、前記ブドウ科ブドウ属の植物は、ブドウであることが好ましい。