Anne-Sophie Brillouet,Marisa DeVita Dufort,Ali Fassih,Devin L. Garcia,Ya-Ping Hu,Wen-Hwa Ting Li,Ramine Parsa,Jyotsna Paturi,Dianne Rossetti,Ying Sun,Janet Wangari-Talbot,Robert Wayne Yates
申请号：
US14806699
公开号：
US10130578B2
申请日:
2015.07.23
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Low pH compositions for topical administration to skin are provided. They comprise a buffering agent having a pKa of about 2.8 to about 4.2 and a cosmetically acceptable active ingredient having a pKa within about 1 unit of the pKa of the buffering agent. The composition has a pH of about 3.3 to 4 and a buffer capacity of at least about 0.15. A method of increasing the topical delivery of a cosmetically acceptable active ingredient having a pKa of about 2.8 to about 4 is also provided.
