БРИЙУЭ Анн-Софи (US),ДЮФОР Мариса ДеВита (US),ФАССИХ Али (US),ГАРСИЯ Девин Л. (US),ХУ Я-Пин (US),ЛИ Вэнь-Хва Тин (US),ПАРСА Рамин (US),ПАТУРИ Джьотсна (US),РОССЕТТИ Дайанн (US),СУНЬ Ин (US),ВАНГАРИ-ТЭ
申请号：
RU2016129158
公开号：
RU2016129158A
申请日:
2016.07.18
申请国别(地区):
RU
年份:
2018
代理人:
摘要：
Low pH compositions for topical administration to skin are provided. They comprise a buffering agent having a pKa of about 2.8 to about 4.2 and a cosmetically acceptable active ingredient having a pKa within about 1 unit of the pKa of the buffering agent. The composition has a pH of about 3.3 to 4 and a buffer capacity of at least about 0.1. A method of increasing the topical delivery of a cosmetically acceptable active ingredient having a pKa of about 2.8 to about 4 is also provided.
