The present invention relates to an intra cardiac echo (ICE) imaging device, an ICE imaging system and method for assessing coronary circulation using an ICE probe. An image (1) of a cardiac region is received, wherein the image provides at least one or more coronary vessels (3) and/or at least one heart chamber (5); at least one region of interest (ROI) (7) within the image is defined; imaging parameters of an ICE probe (9) are received; and at least one of a location, an orientation and access path of the ICE probe relative to the RO is calculated based on anatomical content in the ROI and/or in the cardiac region and the imaging parameters of the ICE probe, wherein the calculated location and/or orientation and/or access path is optimal for imaging of the at least one ROI.