THE PRESENT INVENTION PROVIDES A BENZOAZEPINE COMPOUND REPRESENTED BY FOLLOWING GENERAL FORMULA (1) : OR A SALT THEREOF, WHEREIN R REPRESENTS A HYDROGEN ATOM, A HYDROXYL GROUP OPTIONALLY PROTECTED WITH A PROTECTING GROUP, ETC., R1 REPRESENTS A HYDROGEN ATOM OR HYDROXYL-PROTECTING GROUP, AND X REPRESENTS AN OXYGEN ATOM OR A SULFUR ATOM. THE BENZOAZEPINE COMPOUND OF THE PRESENT INVENTION AND SALTS THEREOF HAVE HIGH SOLUBILITY IN WATER, AND CAN BE SUITABLY USED FOR INJECTIONS.