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COMPOUND OF 3-HYDROXYL PYRIDINE, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE THEREOF
专利权人:
SHENYANG SUNSHINE PHARMACEUTICAL CO. LTD.
发明人:
Yunlong ZHOU,Suixiong CAI,Guangfeng WANG,Lingling JIAO,Ping MIN,Yu JING,Ming GUO
申请号:
US15561435
公开号:
US20180117021A1
申请日:
2015.12.14
申请国别(地区):
US
年份:
2018
代理人:
摘要:
A compound of the following formula (I) or a pharmaceutically acceptable salt thereof, wherein R1 and R2 are independently H; R3 is selected from H, a C1-C7 straight-chain, and a branched or cyclic alkyl; and R4, R5, R6, R7, and R8 are each independently selected from C1-C7 alkyl, halo C1-C7 alkyl and the like. Also provided is a method for preparing the compound, pharmaceutical compositions including the compound or pharmaceutically acceptable salts thereof, and uses of the compound or pharmaceutically acceptable salt thereof in the preparation of a medicine for inhibiting HIF prolyl hydroxylase or a medicine for promoting the generation of endogenous EPO.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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