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Compounds that have hypolipidemic and hypocholesterolemic activities, procedure for their preparation and pharmaceutical compositions containing them
专利权人:
CADILA HEALTHCARE LIMITED
发明人:
LOHRAY, BRAJ,LOHRAY, VIDYA,BAROT, VIJAY
申请号:
ES01921764
公开号:
ES2449194T3
申请日:
2001.01.17
申请国别(地区):
ES
年份:
2014
代理人:
摘要:
A compound represented by the general formula (I): ** Formula ** its tautomeric forms, its stereoisomers, its pharmaceutically acceptable salts and its pharmaceutically acceptable solvates, in which one or more groups R1, R2, R3, R4 may be the same or different and represent hydrogen, halogen, perhaloalkyl, amino, nitro, cyano, amidino, guanidino, substituted or substituted groups selected from: - (C1-C12) alkyl groups; - linear or branched (C2-C12) alkenyl groups; - (C3-C7) cycloalkyl groups; - (C3-C7) cycloalkenyl groups; - bicycloalkyl selected from bicyclooctane, biciclononano and bicyclodecane; bicycloalkenyl selected from cyclooctene, biciclononene and bicyclodecene; - (C1-C12) alkoxy groups; - cyclo (C3-C7) alkoxy groups; - aryl groups selected from phenyl, naphthyl, benzo- [1,3] dioxol or biphenyl groups; - aryloxy groups selected from phenoxy, naphthyloxy, biphenyloxy groups; - aralkyl groups wherein the aryl and alkyl groups are as defined above; - aralkoxy groups wherein the aralkyl group is as defined above; - heteroaryl groups selected from pyridyl, thienyl, furyl, pyrrolyl, oxazolyl, thiazolyl, imidazolyl, oxadiazolyl, tetrazolyl, benzopyranyl, benzofuranyl groups; - heteroalkyl groups selected from furanomethyl, piperidinomethyl, oxazolmethyl, oxazolethyl; - heterocyclyl groups selected from aziridinyl, pyrrolidinyl, piperidinyl; - heterocycloalkyl groups selected from pyrrolidinoalkyl, piperidinoalkyl, morpholinoalkyl, thiomorpholinoalkyl, oxazolinoalkyl; - heterocycloalkoxy groups wherein heterocyclyl and alkoxy group are as defined above; - heteroaryloxy groups wherein the heteroaryl group is as defined above; - heteroaralkoxy groups wherein the heteroaralkyl group is as defined above; - acyl groups selected from acetyl, propionyl or benzoyl groups; - acyloxy groups selected from MeCOO, EtCOO, PhCOO groups; - acylamino groups selected from CH3CONH, C2HsCONH, C3H7CONH, C6H5CONH; - (C1-C6) monoalkylamino groups; - (C1-C6) dialkylamino groups; - aryla
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