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Drug for respiratory diseases
专利权人:
Daiichi Sankyo Company; Limited
发明人:
TAKAHASHI, Sakiko,DOMON, Yuki,KITANO, Yutaka,SHINOZUKA, Tsuyoshi
申请号:
ES14763747
公开号:
ES2663798T3
申请日:
2014.03.13
申请国别(地区):
ES
年份:
2018
代理人:
摘要:
A drug for use in the treatment and / or prevention of a respiratory disease comprising a compound represented by the following formula (I) or a pharmacologically acceptable salt thereof as an active ingredient: ** (See formula) ** in the that Ar1 and Ar2, each independently represent a heteroaryl group or an aryl group, R1, R2 and R3, each independently represent a hydrogen atom, a halogen atom, a C1-C6 alkyl group, a C1-C6 alkyl group halogenated, a hydroxy-C1-C6 alkyl group, a C1-C6 alkoxy-C1-C6 alkyl group, a C3-C7 cycloalkyl group or a cyano group, R4 and R5, each independently represents a hydrogen atom, an atom of halogen, a C1-C6 alkyl group, a halogenated C1-C6 alkyl group, a hydroxyl group, a hydroxy-C1-C6 alkyl group, a C1-C6 alkoxy-C1-C6 alkyl group, a C3-C7 cycloalkyl group or a C1-C6 alkoxy group, and n represents an integer from 1 to 3, and in which the heter group oaryl or aryl optionally has one or two substituents independently selected from a halogen atom, a C1-C6 alkyl group, a halogenated C1-C6 alkyl group, a hydroxyl group, a hydroxy-C1-C6 alkyl group, a C1- alkoxy group C6-C1-C6 alkyl, a C3-C7 cycloalkyl group, a carboxy group, a cyano group, an amino group, a C1-C3 alkylamino group and a C1-C3 di-alkylamino group and, when the heteroaryl or aryl group has Two of these groups, the two groups are the same or different from each other.Un fármaco para su uso en el tratamiento y/o la prevención de una enfermedad respiratoria que comprende un compuesto representado por la siguiente fórmula (I) o una sal farmacológicamente aceptable del mismo como ingrediente activo: **(Ver fórmula)** en la que Ar1 y Ar2, representan cada uno independientemente un grupo heteroarilo o un arilo grupo, R1, R2 y R3, representan cada uno independientemente un átomo de hidrógeno, un átomo de halógeno, un grupo alquilo C1-C6, un grupo alquilo C1-C6 halogenado, un grupo hidroxi-alquilo C1-C6, un grupo alcoxi C1-C6-alquilo C1-C6, un grupo cicloalquilo C3-C7 o un grupo ciano,
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