COMPOUND OF 5-HYDROXYL-1,7-NAPHTHYRIDINE SUBSTITUTED BY ARYL OR HETEROARYL, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE THEREOF

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专利权人:

发明人:

申请号：

EP15887309.1

公开号：

EP3287456A1

申请日:

2015.12.14

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

Disclosed are a compound of the following formula (I) or a pharmaceutically acceptable salt thereof, a preparation method thereof, pharmaceutical compositions and uses thereof in the preparation of a medicine for inhibiting HIF prolyl hydroxylase or a medicine for promoting the generation of endogenous EPO, wherein in the formula (I), R1 and R2 are each independently hydrogen R3 is hydrogen or C1-3 alkyl and Ar is an aromatic ring or an heteroaromatic ring selected from a naphthalene ring, a pyridine ring, a thiophene ring, a furan ring and a substituted benzene ring.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/