Ricardo Andres Ceriani Fernandez;Fernando Antonio Albornoz Marquez;Cristian Andr;Miguel Angel Fuentes Chandia;Donald Irving Brown Gonzalez;Carolina Ruth Weinstein Oppenheimer;Manuel Eduardo Young Anze
发明人:
Manuel Eduardo Young Anze,Carolina Ruth Weinstein Oppenheimer,Donald Irving Brown Gonzalez,Miguel Angel Fuentes Chandia,Ricardo Andres Ceriani Fernandez,Fernando Antonio Albornoz Marquez,Cristian Andr
申请号:
US14235909
公开号:
US20140242181A1
申请日:
2012.08.03
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention aims to generate a fibrin gel for cell proliferation and transport using the patient's own blood or compatible blood. The gel-preparation process consists in taking a quantity of blood from the patient, using sodium citrate as anticoagulant, separating off the citrated plasma by centrifugation, and resuspending the cells to be transported in the plasma. CaCl2 is added to the resulting suspension to form the gel (either as an isolated coagulate or within a porous chitosan, gelatin or hyaluronic acid matrix), and the gel is cultured in an incubator to promote cell growth. The invention will be of use in cell growth for the purposes of implantation in cutaneous, cartilaginous, gingival and bone lesions, inter alias, and in the field of tissue engineering.