INTITUTO PARA EL DESARROLLO BIOTECNOLÓGICO Y LA INNOVACIÓN S.A.
发明人:
CAROLINE RUTH WEINSTEIN OPPENHEIMER,CRISTIAN ANDRÉS ACEVEDO GUITIÉRREZ,DONALD IRVING BROWN GONZÁLEZ,FERNANDO ANTONIO ALBORNOZ MÁRQUEZ,MANUEL EDUARDO YOUNG ANZE,MIGUEL ÁNGEL FUENTES CHANDÍA,RICARDO AND
申请号：
BR112014002628
公开号：
BR112014002628A2
申请日:
2012.08.03
申请国别(地区):
BR
年份:
2017
代理人:
摘要：
The present invention aims to generate a fibrin gel for cell proliferation and transport using the patient's own blood or compatible blood. The gel-preparation process consists in taking a quantity of blood from the patient, using sodium citrate as anticoagulant, separating off the citrated plasma by centrifugation, and resuspending the cells to be transported in the plasma. CaCl 2 is added to the resulting suspension to form the gel (either as an isolated coagulate or within a porous chitosan, gelatin or hyaluronic acid matrix), and the gel is cultured in an incubator to promote cell growth. The invention will be of use in cell growth for the purposes of implantation in cutaneous, cartilaginous, gingival and bone lesions, inter alia, and in the field of tissue engineering.
