An antimicrobial system, including a luminaire. The luminaire includes a first disinfection light source to emit a first disinfection light in a first ultraviolet (UV) band for disinfecting an occupied space of a plurality of pathogens that are exposed to the first disinfection light, the first UV band being 200 nanometers (nm) to 250 nm principal wavelength. The luminaire also includes a second disinfection light source to emit a second disinfection light in a second UV band for disinfecting an unoccupied space of the plurality of pathogens that are exposed to the second disinfection light, the second UV band being 200 nm to 400 nm principal wavelength. The antimicrobial system also includes a disinfection light control device to generate a control signal to control emission of the first disinfection light and the second disinfection light.