Thomas D. Aicher,Kenneth Jay Barr,Vladimir Simov,William D. Thomas,Peter L. Toogood,Chad A. Van Huis
申请号：
US14398068
公开号：
US09266827B2
申请日:
2013.05.03
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The invention provides bicyclic sulfone compounds, pharmaceutical compositions, methods of inhibiting RORy activity, reducing the amount of iL-17 in a subject, and treating immune disorders and inflammatory disorders using such bicyclic sulfone compounds. Another aspect of the invention provides a method of treating a subject suffering from a medical disorder. The method comprises administering to the subject a therapeutically effective amount of one or more bicyclic sulfone compounds described herein. In certain other embodiments, the disorder is rheumatoid arthritis.
