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Bicyclic sulfone compounds for inhibition of RORy activity and the treatment of disease
专利权人:
Merck Sharp & Dohme Corp.;Lycera Corporation
发明人:
Aicher, Thomas,Barr, Kenneth,Simov, Vladimir,Thomas, William,Toogood, Peter,Van Huis, Chad
申请号:
AU2013259904
公开号:
AU2013259904A1
申请日:
2013.05.03
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
The invention provides bicyclic sulfone compounds, pharmaceutical compositions, methods of inhibiting RORy activity, reducing the amount of iL-17 in a subject, and treating immune disorders and inflammatory disorders using such bicyclic sulfone compounds. Another aspect of the invention provides a method of treating a subject suffering from a medical disorder. The method comprises administering to the subject a therapeutically effective amount of one or more bicyclic sulfone compounds described herein. In certain other embodiments, the disorder is rheumatoid arthritis.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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