AICHER THOMAS,BARR KENNETH,SIMOV VLADIMIR,THOMAS WILLIAM,TOOGOOD PETER,VAN HUIS CHAD
申请号:
IN8025DEN2014
公开号:
IN8025DEN2014A
申请日:
2014.09.25
申请国别(地区):
IN
年份:
2015
代理人:
摘要:
The invention provides bicyclic sulfone compounds pharmaceutical compositions methods of inhibiting RORy activity reducing the amount of iL-17 in a subject and treating immune disorders and inflammatory disorders using such bicyclic sulfone compounds. Another aspect of the invention provides a method of treating a subject suffering from a medical disorder. The method comprises administering to the subject a therapeutically effective amount of one or more bicyclic sulfone compounds described herein. In certain other embodiments the disorder is rheumatoid arthritis.