CAI XIONG,QIAN CHANGGENG,ZHAI HAIXIAO,LAI CHENGJUNG,BAO RUDI
申请号：
NZ61558612
公开号：
NZ615586A
申请日:
2012.03.30
申请国别(地区):
NZ
年份:
2015
代理人:
摘要：
Disclosed is the compound of Formula I wherein R is hydrogen or an acyl group, particularly N-hydroxy-2-(((2-(6-methoxypyridin-3-yl)-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)(methyl)amino)pyrimidine-5-carboxamide. Also disclosed are pharmaceutical compositions comprising such compounds and the use of such compounds in the the manufacture of medicaments for treatment of phosphoinositide 3 -kinase related diseases and disorders such as cancer. The instant application further relates to the the treatment of histone deacetylase related disorders and diseases related to both histone deacetylase and phosphoinositide 3-kinase.
