KYOTO UNIVERSITY;TATSUYA KAWAMOTO;YUKIKO YAMAGISHI;KENJI OSAFUNE;ASTELLAS PHARMA INC.
发明人:
TATSUYA KAWAMOTO,YUKIKO YAMAGISHI,KENJI OSAFUNE
申请号:
IL25797418
公开号:
IL257974D0
申请日:
2018.03.08
申请国别(地区):
IL
年份:
2018
代理人:
摘要:
An object of the present invention resides in providing a method for acquiring and producing high-purity renal progenitor cells from a renal progenitor cell population into which pluripotent stem cells are induced to differentiate, by identifying a cell surface antigen marker specific to renal progenitor cells. A method for producing renal progenitor cells into which pluripotent stem cells are induced to differentiate, the method comprising the steps of: (i) culturing the pluripotent stem cells under conditions that induce differentiation into renal progenitor cells; and (ii) sorting a cell population from the cells obtained at step (i), by using at least one cell surface marker selected from the group consisting of CD9(-), CD55(-), CD106(+), CD140a(+), CD140b(+), CD165(+), CD271(+) and CD326(-).