Nucleosides of the general formula I ** Formula ** with R1>； = halogen, R2 selected from the group consisting of H, halogen, OR8, CN, N3, NR6R7 and prodrug radicals linked through an oxygen atom, wherein the Prodrug radical is selected from the group consisting of ** Formula ** with R10 and R11, independently of each other, straight or branched chain C1-C8 alkyl, aryl, which may also have heteroatoms, R12>； = C1-C8 alkyl straight or branched chain, aralkylene, aryl, which may also have heteroatoms, R13>； = straight or branched chain C1-C8 alkyl, ** Formula ** with R10 and R11, independently of each other, C1-C8 alkyl linear or branched chain, aryl, which may also have heteroatoms, R12>； = straight or branched chain C1-C8 alkyl, aralkylene, aryl, which may also have heteroatoms, R13>； = straight or branched chain C1-C8 alkyl, R14 >； = O-C1-C8 alkyl, NH-C1-C8 alkyl, N- (C1-C8 alkyl) 2, ** Formula a ** with R15>； = C1-C8 straight or branched chain alkyl, ** Formula ** with R15>； = C1-C8 straight or branched chain alkyl, R16>； = C1-C8 straight or branched chain alkyl, OR -aryl ** Formula ** with R17>； = C1-C8 straight or branched chain alkyl, halogen, ** Formula ** with R18>； = C1-C8 straight or branched chain alkyl, aryl or heteroaryl, R19>； = alkyl -CO-, aryl-CO-, amino acid or peptide, with R20>； = straight-chain or branched C1-C8 alkyl, R3>； = H, straight-chain or branched C1-C8 alkyl, straight-chain C1-C8 alkylene or branched, R4>； = H, halogen, OR8, N3, NR6R7 or R4 together with R1 represent a second link between C atoms adjacent to R1 and R4, R5>； = H, C1-C8 alkyl or aryl and R6, R7 and R8, independently of each other, H, C1-C8 straight or branched chain alkyl or acetyl, the compounds with the following radicals being excluded: R1>； = F, R2>； = OH, R3>； = R4>； = R5>； = H, R1>； = F, R2>； = O-acetyl, R3>； = R4>； = R5>； = H, R1>； = F, R2 >； = triphosphate, R3>； = R4>； = R5>； = H, R1>； = Cl, R2>； = OH,
