Pharmaceutical composition for preventing or treating autoimmune diseases comprising cedrol or derivatives thereof, or pharmaceutically acceptable salts thereof
University of Seoul Industry Cooperation Foundation
发明人:
Ha Won Kim,Dong Hee Lee
申请号：
US15945606
公开号：
US10493043B2
申请日:
2018.04.04
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention relates to a pharmaceutical composition for preventing or treating autoimmune diseases having cedrol or a pharmaceutically acceptable salt thereof as an active ingredient. Particularly, the cedrol or the derivative thereof of the present invention inhibits the expression of IL-17A, and in particular, cedrol, cedryl acetate, and cedrene exhibit the effect of delaying the outbreak of psoriasis and treating thereof in a psoriasis animal model. Therefore, these compounds can be used for the treatment of autoimmune diseases mediated by IL-17.
