NOVEL QUINOLINONE DERIVATIVE AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING ALLERGIC DISEASES SUCH AS ASTHMA OR ATOPIC DERMATITIS INCLUDING THE QUINOLINONE DERIVATIVE AS ACTIVE INGREDIENT
Korea University Research and Business Foundation; Sejong Campus
发明人:
Youngjoo BYUN,Young Ho JEON,Kiho LEE,Ki Yong LEE,Yong Woo JUNG,Sang-Hyun SON
申请号：
US16473362
公开号：
US20200140457A1
申请日:
2018.01.04
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention relates to anovel quinolinone derivative compound that regulates intracellular signal transduction mediated by TSLP and IL-33 to exhibit efficacy in preventing or treating allergic diseases such as asthma or atopic dermatitis. The quinolinone derivative compound of the present invention can effectively suppress inflammatory responses of allergic diseases such as asthma or atopic dermatitis. The present invention also relates to a pharmaceutical composition including the quinolinone derivative compound. The pharmaceutical composition of the present invention can be used to fundamentally prevent or treat various allergic and asthmatic diseases.
