PYRAZOLOPYRIMIDINE DERIVATIVES, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR USE IN PREVENTING OR TREATING CANCER, AUTOIMMUNE DISEASE AND BRAIN DISEASE CONTAINING THE SAME AS AN ACTIVE INGREDIENT
Pilho Kim,Sung Yun Cho,Jae Du Ha,Hyoung Rae Kim,Jong Yeon Hwang,Chang Soo Yun,Hee Jung Jung,Chi Hoon Park,Chong Ock Lee,Chang Hoon Lee,Sunjoo Ahn
申请号：
US16612592
公开号：
US20200199129A1
申请日:
2018.05.14
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention relates to a pyrazolopyrimidine derivative, a preparation method thereof and a pharmaceutical composition comprising the same as an active ingredient for the prevention or treatment of cancer, autoimmune disease and brain disease. The pyrazolopyrimidine derivative of the present invention exhibits excellent Bruton's tyrosine kinase inhibition activity, so that it can be effectively used as a pharmaceutical composition for the prevention or treatment of cancer, autoimmune disease and Parkinson's disease.
