PROBLEM TO BE SOLVED: To provide a stylet having a freeze-dried medical solution filled inside.SOLUTION: A stylet 10 is prepared, which includes a needle-like part 102 on one surface of a substrate, and includes a hollow hole 103 in the needle-like part. Thereafter, a tip part of the needle-like part 102 is subjected to a water repellent treatment, then the stylet 10 and a medical solution are arranged under a reduced pressure, and the hollow hole 103 of the stylet 10 is brought into contact with a liquid surface of the medical solution. In the state where the hollow hole 103 of the stylet 10 has a contact with the liquid surface of the medical solution, the atmospheric pressure (first pressure) is given again, to thereby fill the hollow hole 103 with the medical solution. Then, the medical solution filled in the hollow hole 103 is frozen and dried.SELECTED DRAWING: Figure 3COPYRIGHT: (C)2016,JPO&INPIT【課題】内部に凍結乾燥された薬液が充填された針状体を提供する。【解決手段】基板の一方の面に針状部102を備え、該針状部に中空孔103を備える針状体10を用意する。そして、針状部102の先端部に撥水処理した後、針状体10及び薬液を減圧下に配置して、針状体10の中空孔103と薬液の液面を接触させ、針状体10の中空孔103と薬液の液面を接触させた状態で大気圧(第1の圧力)とすることで、中空孔103に薬液を充填する。その後、中空孔103に充填された薬液を凍結乾燥する。【選択図】図3