Herbert Andres,David Casagolda Vallribera,Hartmut Duefel,Michael Gerg,Christian Scholz,Michael Schraeml
申请号：
US14112108
公开号：
US09266962B2
申请日:
2012.05.04
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Herein is reported a fusion polypeptide according to formula (I): NH2—S2—X1—S1—COOH, wherein X1 comprises either a random amino acid sequence or an amino acid sequence derived from a first polypeptide, S2 and S1 are non-overlapping amino acid sequences derived from a second polypeptide, and denotes a peptide bond, wherein the second polypeptide is a polypeptide with peptidyl-prolyl cis/trans-isomerase activity (PPIase activity) or is derived from the FKBP-fold domain family, wherein X1 is inserted in place of the insert-in-flap-domain of the second polypeptide.
