Herbert Andres,David Casagolda Vallribera,Hartmut Duefel,Michael Gerg,Christian Scholz,Michael Schraeml
申请号：
US15924110
公开号：
US10647765B2
申请日:
2018.03.16
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Herein is reported a fusion polypeptide according to formula INH2—；S2—；X1—；S1—；COOH ； ；(formula I)whereinX1 comprises either a random amino acid sequence or an amino acid sequence derived from a first polypeptide,S2 and S1 are non-overlapping amino acid sequences derived from a second polypeptide, and—； denotes a peptide bond,wherein the second polypeptide is a polypeptide with peptidyl-prolyl cis/trans-isomerase activity (PPIase activity) or is derived from the FKBP-fold domain family, wherein X1 is inserted in place of the insert-in-flap-domain of the second polypeptide.
